Heinz Body Formation in Calf Erythrocytes

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Heinz Body Phenomenon in Erythrocytes

MONG the early investigators of hemolytic substances were Casper and Hoppe’ who in 1859 observed the brown coloration of blood due to nitrobenzene. Since then there has been a continued interest in the action of such toxic materials on the formed elements of the blood. The accelerated development of synthetic organic chemistry during the latter half of the i9th Century created numerous industri...

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Heinz Body Phenomenon in Erythrocytes

MONG the early investigators of hemolytic substances were Casper and Hoppe’ who in 1859 observed the brown coloration of blood due to nitrobenzene. Since then there has been a continued interest in the action of such toxic materials on the formed elements of the blood. The accelerated development of synthetic organic chemistry during the latter half of the i9th Century created numerous industri...

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Heinz Body Formation in the New

ER5 Helen W. Belding,M.D., Winston-Salem, N. C. Conrad Maier, M.D., Zurich, Switzerland Sheila T. Callender,M.D.,Oxford, England Milos Netou ek,M.D.,Prague, Czechoslovakia Robert B. Chodos M.D. Framingham Mass. Charles E. Rath, M.D., Washington . . . Jean P. Soulier M.D. Paris France Roger C. Crafts, Ph.D., Cincinnati , RamonM.Su#{225}rez M.D. SanJuan PuertoRrco C. R. DasGupta, M.D., Calcutta, ...

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Membrane protein lesions in erythrocytes with Heinz bodies.

We studied Heinz body-containing erythrocytes with three different unstable hemoglobins: Nottingham, Brockton, and unclassified. We demonstrated two classes of membrane protein defects in unstable hemoglobin-containing cells (UH-RBCs), a defect of the spectrin-depleted inside-out vesicle (UH-IOV), and a defect of spectrin (UH-spectrin) itself. The composition of UH-IOVs is the same as control w...

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Studies of hemoglobin denaturation and Heinz body formation in the unstable hemoglobins.

The sequential changes that occur during the precipitation on mild heating of the unstable hemoglobins, Hb Christchurch, Hb Sydney, Hb Köln, and Hb A, were examined with particular attention to the possibility of an accompanying oxidative process. Hb Christchurch, Hb Sydney, and Hb A precipitated with equal amounts of alpha- and beta-chains and full heme complement. Hb Köln, however, was one-ha...

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ژورنال

عنوان ژورنال: Journal of Dairy Science

سال: 1978

ISSN: 0022-0302

DOI: 10.3168/jds.s0022-0302(78)83701-1